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Cayman Chemical ANTIBODY PHA-543613 100mg

Supplier: Cayman Chemical 42222100 MG

A σ1 receptor ligand and dopaminergic stabilizer binds to the σ1 receptor and dopamine D2 receptor in the high-affinity state (Kis 81.3 and 7521 nM respectively) increases striatal DOPAC levels and locomotor activity as well as inhibits amphetamine-induced locomotor activity in rats at 100 Umol/kg improves motor function and reduces striatal mHtt aggregates in the R6/2 mouse model of Huntingtons disease at 5 or 6 mg/kg prevents muscle atrophy and the loss of innervated neuromuscular junctions in the SOD1-G93A mouse model of ALS at 30 mg/kg
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