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Cayman Chemical ANTIBODY PS-10 5mg

Supplier: Cayman Chemical 420685 MG
A PDHK inhibitor (IC50s = 2.07, 0.8, 21.3, and 0.77 µM for PDHK1, -2, -3, and -4, respectively); selectively binds to PDHK2 over Hsp90 (Kds = 0.239 and 47 µM, respectively); increases heart, liver, and kidney pyruvate dehydrogenase complex activity, decreases blood glucose levels in a glucose tolerance test, and reduces plasma lactate, cholesterol, and triglyceride levels, fat mass, and hepatic lipid accumulation in a mouse model of high-fat diet-induced obesity at 70 mg/kg
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