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Cayman Chemical ANTIBODY PTIQ 50mg
Supplier: Cayman Chemical 3354050 MG
A neuroprotective compound; inhibits tetrahydro-L-biopterin-induced cytotoxicity and increases in MMP-3 in CATH.a cells (IC50s = 1.8 and 0.06 µM, respectively); inhibits LPS-induced production of MMP-3, TNF-α, and COX-2 in BV-2 microglia (IC50s = 2.4, 6.5, and 9.3 µM, respectively); increases survival of striatal nigral dopaminergic neurons, reduces microglial activation, and alleviates motor deficits in a mouse model of MPTP-induced Parkinson’s disease at 3 and 30 mg/kg
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