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Cayman Chemical ANTIBODY QuInInIb 500ug
Supplier: Cayman Chemical 19838500 UG
A CysLT1 and CysLT2 receptor antagonist (IC50s = 1.4 and 52 µM, respectively); inhibits tubule formation in HMEC-1 cells at 3.16 and 10 µM; inhibits sprout formation in isolated mouse aortic rings at 10 µM; decreases angiogenesis in an oxygen-induced retinopathy mouse model of ocular angiogenesis, preventing revascularization at 0.5 and 3 µM, as well as increasing neovascularization and vascular density at 3 µM; reduces tumor growth and inhibits angiogenesis in an HT-29 colorectal cancer mouse xenograft model at 50 mg/kg every three days
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