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Cayman Chemical ANTIBODY SPHINX31 1mg
Supplier: Cayman Chemical 215821 MG
A potent inhibitor of SRPK1 (IC50 = 5.9 nM); inhibits phosphorylation of SRSF1, an SRPK1 substrate, in PC3 cells (EC50 = 360 nM); increases expression of the anti-angiogenic VEGF-A165b splice variant in RPE cells; inhibits blood vessel growth and macrophage infiltration in the eyes of a mouse model of choroidal neovascularization (2 μg per eye)
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