Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Cayman Chemical ANTIBODY STX140 5mg
Supplier: Cayman Chemical 278635 MG
An estrogen sulfamate with anticancer activities; inhibits steroid sulfatase (IC50s = 39 and 0.5 nM in placental microsomes and MCF-7 cancer cells, respectively); binds to carbonic anhydrase IX and II (Kis = 70 and 270 nM, respectively); inhibits bovine brain tubulin assembly in a cell-free assay (IC50 = 2.2 µM) and tubule formation in HUVECs at 50 and 100 nM; inhibits proliferation of LNCaP, PC3, and MDA-MB-231 cancer cells, as well as wild-type A2780 cancer cells and adriamycin- and cisplatin-resistant A2780 cancer cells (IC50s = 530, 400, 618, 330, 870, and 380 nM, respectively); reduces angiogenesis in a Matrigel™ plug assay in mice and tumor growth in MCF-7 and MDA-MB-231 mouse xenograft models at 20 mg/kg
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?