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Cayman Chemical ANTIBODY TDI-10229 25mg
Supplier: Cayman Chemical 3767425 MG
A soluble adenylyl cyclase inhibitor (IC50 = 0.2 µM for the human enzyme in a cell-free assay); selective for sAC over AC1-3, -5, -8, and -9 at 10 µM; inhibits cAMP accumulation induced by IBMX in rodent sAC-expressing HEK293 cells (IC50 = 0.1 µM); inhibits capacitation-induced cAMP accumulation and PKA activation in isolated mouse and human sperm at 5 µM; prevents the acrosome reaction and fertilization of mouse sperm with mouse oocytes in vitro at 5 and 50 µM
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