Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Cayman Chemical ANTIBODY TH-302 25mg
Supplier: Cayman Chemical 2219525 MG
A hypoxia-activated prodrug and DNA alkylating agent with anticancer activity; selectively cytotoxic to H460 human NSCLC cells grown under hypoxic over normoxic conditions (IC50s = 0.019 and 5.1 μM, respectively); reduces survival of H460 and HT-29 cells in a clonogenic assay (IC50s = 0.2 and 0.2 μM, respectively); inhibits primary tumor growth by 41% in an MIA PaCa-2-RFP mouse orthotopic xenograft model at 33 mg/kg per day; inhibits tumor growth in the Calu-6 NSCLC, H82 small cell lung, A375 melanoma, PC-3 prostate, and BxPC-3 pancreatic cancer mouse xenograft models at 50 mg/kg
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?