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Cayman Chemical ANTIBODY UC2288 5mg
Supplier: Cayman Chemical 373805 MG
A p21WAF1 inhibitor; reduces the protein levels and mRNA expression of p21WAF1 independently of Raf and p53, respectively, at 10 µM; decreases the proliferation of, and phosphorylation of EGFR and ERK1/2 in, CNE-2 and 5-8F cell lines at 8 µM; reduces tumor growth and induces apoptosis in an HCT116 colorectal cancer mouse xenograft model at 15 mg/kg three times per week in combination with imetelstat
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