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Cayman Chemical ANTIBODY VorucIclIb 1mg
Supplier: Cayman Chemical 290851 MG
A pan-CDK inhibitor (Kis = 0.626-9.1 nM); selective for CDKs over MAK and ICK (Kis = 259 and 481 nM, respectively), in a panel of 48 kinases; decreases Mcl-1 levels and increased cleaved PARP levels in six DLBCL cell lines at 0.5-5 µM; reduces tumor growth by 56.3% in a Ri-1 mouse xenograft model at 200 mg/kg
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