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Cayman Chemical ANTIBODY VX-765 5mg
Supplier: Cayman Chemical 288255 MG
A prodrug form of VRT-043198; inhibits LPS-induced increases in serum IL-1β levels in mice at 50, 100, and 200 mg/kg; reduces oxazolone-induced EAr edema and levels of IL-1β, IL-18, and IFN-γ in EAr tissue in an oxazolone-sensitized mouse model of delayed-type hypersensitivity; reduces forepaw inflammation in a mouse model of collagen-induced arthritis in a dose-dependent manner; decreases seizure duration and the number of seizures in a mouse model of acute seizures induced by hippocampal kainic acid injection at ≥50 mg/kg, as well as delays the onset of seizures at 100 and 200 mg/kg; reduces the aggregated duration of epileptic activity in a mouse model of chronic epilepsy
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