Learn More
Cayman Chemical ANTIBODY ZIbotentn 1mg

Supplier: Cayman Chemical 237021 MG
A selective ETA receptor antagonist (IC50s = 21 and >10,000 nM for human recombinant ETA and ETB, respectively); inhibits ET-1-induced growth of HEY, OVCA 433, SKOV3, and A2780 cells in vitro; reduces ET-1-induced expression of MMP-2, MMP-9, VEGF, COX-1 and COX-2 in HEY cells; reduces tumor growth in an HEY mouse xenograft model in a dose-dependent manner (10-50 mg/kg per day)
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.