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Aobious Inc AOBIOUS USP7 Inhibitor, Non-covalent, Selective, 98% HPLC
Supplier: Aobious Inc AOB378555MG
FT671 is a potent, non-covalent, and selective inhibitor of Ubiquitin-Specific Protease 7 (USP7), a deubiquitinating enzyme involved in regulating various cellular processes, including protein stability and signaling pathways.
- Potent, non-covalent, and selective inhibitor of USP7.
- Binds to the catalytic domain of USP7, inhibiting its deubiquitinating activity.
- IC50 of approximately 52 nM; dissociation constant (Kd) of 65 nM.
- Stabilizes p53 by inhibiting USP7, leading to increased p53 levels.
- Induces G1 phase arrest and apoptosis in various cancer cell lines.
- Effective in preclinical models for cancer research, delaying tumor growth.
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