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ABclonal Technology AP0387-1000ul Phospho-LIMK1-T5
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Supplier:  ABclonal Technology AP03871000UL

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LIM proteins containing conserved LIM domains with zinc fingers mediate protein-protein interactions LIM kinase-1 (LIMK1) belongs to a subfamily with two N-terminal LIM motifs and a C-terminal kinase domain LIMK1 is a serine/threonine kinase that regulates actin polymerization by phosphorylating and inactivating cofilin an actin-binding factor It is widely expressed during development and is involved in cellular processes related to cytoskeletal structure LIMK1 also promotes axon growth and may play a role in brain development Hemizygosity of LIMK1 is linked to impaired visuospatial cognition in Williams syndrome Alternative splicing generates multiple transcript variants encoding distinct isoforms

Catalog No. 50-001-13484


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