ABclonal Technology Phospho-Ezrin-Thr567/Radixin-Thr564/Moesin-Thr558 Rabbit pAb

Supplier:  ABclonal Technology AP12841000UL

This gene encodes a cytoplasmic peripheral membrane protein that functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, it links the plasma membrane and the actin cytoskeleton, playing a key role in cell adhesion, migration, and organization. It has been implicated in various cancers. A pseudogene for this gene is located on chromosome 3. Radixin, similar to ezrin and moesin, is important for linking actin to the plasma membrane and is localized to 11q23. Truncated versions of radixin, such as pseudogene RDXP2, are found on Xp21.3, while RDXP1 is mapped to 11p. Multiple alternatively spliced variants encoding different isoforms have been identified. Moesin, another ERM family member, is important for cell movement and recognition.

Catalog No. 50-001-11194