Apexbio Technology LLC AP20187 195514-80-8 50mg

Supplier:  Apexbio Technology LLC B127450

AP20187 (CAS 195514-80-8) is a small molecule dimerizer commonly employed as a chemical inducer of dimerization (CID) in conditional gene expression systems Upon administration AP20187 promotes controlled protein-protein interactions by inducing engineered fusion proteins to dimerize enabling selective activation of signaling pathways In vivo studies demonstrate that AP20187-mediated CID enhances the proliferation of transduced erythrocytes platelets and to a lesser extent granulocytes Additionally AP20187 is utilized in AP20187 LFv2IRE systems activating chimeric insulin receptors which subsequently increases hepatic glycogen levels and promotes glucose uptake in skeletal muscle Such regulated activation systems have significant potential in gene therapy and metabolic research

Catalog No. 50-101-5375