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Apexbio Technology LLC Apelin-13 217082-58-1 25mg
Supplier: Apexbio Technology LLC C363325
Apelin-13 (CAS 217082-58-1) is an endogenous peptide ligand targeting the APJ receptor a G-protein-coupled receptor (GPCR) implicated in cardiovascular regulation fluid balance and as a co-receptor for HIV entry Apelin-13 activates APJ receptors with high potency exhibiting an EC50 around 0 37 nM In animal studies microinjection into brainstem regions modulates respiratory drive and blood pressure Clinically apelin-13 infusions can induce vasodilation elevate cardiac index and decrease systemic vascular resistance highlighting its utility in cardiovascular and neurophysiological research
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