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Medchemexpress LLC Apilimod (mesylate) | 870087-36-8 | 99.8% | 610.70 | 1 ML
Supplier: Medchemexpress LLC HY14644A10MM/1ML
Apilimod (STA 5326) mesylate is a potent IL-12/IL-23 inhibitor, strongly inhibiting IL-12 with IC50s of 1 nM and 2 nM in IFN-γ/SAC-stimulated human and monkey PBMCs. It is also a potent and highly selective PIKfyve inhibitor.
- Potent IL-12/IL-23 inhibitor
- Strongly inhibits IL-12
- Potent and highly selective PIKfyve inhibitor
- Inhibits IFN-γ production in human PBMCs
- Reduces severity of experimental autoimmune uveoretinitis (EAU)
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