Medchemexpress LLC Apostatin-1 | 2559703-06-7 | 99.8% | 345.50 | C19H27N3OS | 5 MG

Supplier:  Medchemexpress LLC HY1340505MG

Apostatin-1 is a small-molecule research compound that potently inhibits TRADD-mediated signaling, modulates ubiquitination pathways, induces autophagy, and blocks apoptosis in cellular and animal models. It is supplied as a white to off-white solid with manufacturer-recommended storage and solubility guidance for laboratory use.

• Potent TRADD inhibitor that disrupts TRADD interactions.
• Binds TRADD-N with KD = 2.17 μM.
• Inhibits bortezomib-induced apoptosis (IC50 = 0.97 μM).
• Induces autophagy and promotes degradation of long-lived proteins at 10 μM (6 h).
• Soluble in DMSO at 83.33 mg/mL with ultrasonic warming and pH adjustment as recommended.
• Stable as a powder at -20°C for up to 3 years; store solutions frozen per guidance.
• High purity (>99.8%) suitable for research applications.

Catalog No. 50-002-62544