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Medchemexpress LLC Aprindine hydrochloride | 33237-74-0 | 99.0% | C22H31ClN2 | 50 MG
Supplier: Medchemexpress LLC HYA0236A50MG
Aprindine hydrochloride is an Ib-class anti-arrhythmic agent. It primarily blocks sodium channels (INa) and significantly inhibits delayed potassium currents, helping to prolong the atrial effective refractory period (AERP) and prevent atrial fibrillation. It also regulates intracellular calcium ion concentration by inhibiting the Na+/Ca2+ exchange current (INCX), further stabilizing cardiac electrical activity. It is used in the study of atrial fibrillation (AF) and ventricular arrhythmias.
- Functions as an Ib-class anti-arrhythmic agent.
- Blocks sodium channels (INa) and inhibits delayed potassium currents.
- Regulates intracellular calcium ion concentration by inhibiting Na+/Ca2+ exchange current (INCX).
- Used for studying atrial fibrillation (AF) and ventricular arrhythmias.
- Inhibits proliferation of bone marrow cells and human lymphocytes.
- Demonstrates anti-arrhythmic effects in vivo.
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