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Cayman Chemical ArecaIdIn but-2-ynyl ester 5mg

Supplier: Cayman Chemical 398165 MG
A muscarinic acetylcholine receptor agonist; binds to M1, M2, and M3 mChARs (pD2s = 7.93, 8.33, and 7.67, respectively); inhibits calcium channel currents in a whole-cell patch clamp assay using primary rat SPG cells (EC50 = 3.6 µM); inhibits transmural nerve stimulation-induced vasodilation in isolated and washed porcine basilar arterial rings (EC50 = 0.5 µM); reduces MAP and BPM in normotensive rats in a dose-dependent manner
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