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Abcam Asenapine maleate, 5-HT receptor antagonist and D2 antagonist, 10MG
Supplier: Abcam AB12057610MG
MW 401.85 g/mol, Purity >99%. Novel, multiple receptor antagonist. Displays activity at 5-HT, dopamine, adrenoceptors and histamine receptors. (pKi values are 8.60 (5-HT₁A), 8.40 (5-HT₁B), 10.15 (5-HT₂A), 9.75 (5-HT₂B), 10.46 (5-HT₂C), 8.84 (5-HT₅A), 9.60 (5-HT₆), 9.94 (5-HT₇), 8.85 (D₁), 8.90 (D₂L), 8.84 (D₂S), 9.38 (D₃), 8.95 (D₄), 8.93 (α₁A), 8.9 (α₂A), 9.49 (α₂B), 8.91 (α₂C), 9.00 (H₁) and 8.21(H₂)). Increases dopamine, norepinephrine and acetylcholine efflux. Antipsychotic in vivo.
The product is subject to the following: Abcam Restricted Use Statement
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