Medchemexpress LLC Asperuloside | 14259-45-1 | MFCD31725921 | 414.36 | 20 MG

Supplier:  Medchemexpress LLC HYN138220MG

Asperuloside is an iridoid isolated from Hedyotis diffusa, with anti-inflammatory activity. It inhibits inducible nitric oxide synthase (iNOS) and suppresses NF-κB and MAPK signaling pathways.

• Anti-inflammatory activity.
• Inhibits inducible nitric oxide synthase (iNOS).
• Suppresses NF-κB and MAPK signaling pathways.
• Inhibits productions of NO, PGE2, TNF-α and IL-6 in LPS-induced RAW 264.7 cells (In Vitro).
• Inhibits cell viability and induces ER stress-dependent apoptosis in leukemia cell lines (U937, HL-60, AML) (In Vitro).
• Reduces food intake, body weight, and adipose masses in rats consuming a high fat diet (HFD) (In Vivo).
• Inhibits tumor growth of U937 xenografts mice model (In Vivo).
• Relieves LPS-induced acute lung injury via inhibiting MAPK and NF-κB signaling in BALB/c mice (In Vivo).

Catalog No. 50-004-16269