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Medchemexpress LLC Astringin (trans-Astringin) | 29884-49-9 | 5 MG

Supplier: Medchemexpress LLC HYN40935MG
Astringin (trans-Astringin) is an orally active natural flavonoid compound with multiple activities including anti-oxidation, anti-inflammation, anti-apoptosis, and ferroptosis inhibition. It is utilized in research for diseases such as acute lung injury, where it inhibits the production of oxidative stress and inflammatory factors.
- Orally active natural flavonoid compound
- Exhibits anti-oxidation, anti-inflammation, and anti-apoptosis activities
- Functions as an inhibitor of ferroptosis
- Suppresses the elevation of reactive oxygen species (ROS) and malondialdehyde (MDA)
- Reduces inflammatory factors like TNF-α, IL-1β, and IL-6
- Inhibits PI3K/AKT/NF-κB and TLR4/MyD88/HMGB1/RAGE pathways
- Enhances cell viability and inhibits apoptosis in vitro
- Alleviates chromium-induced oxidative stress, inflammation, and renal tissue damage in vivo
- Improves renal function and restores biochemical parameters
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