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TARGETMOL CHEMICALS INC Xevinapant 10mg
SDP

Supplier:  TARGETMOL CHEMICALS INC T676310MG

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AT406 (SM-406, ARRY-334543) is a potent Smac mimetic and an antagonist of IAP (inhibitor of apoptosis protein via E3 ubiquitin ligase), binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3 with Ki of 66.4 nM, 1.9 nM, and 5.1 nM, 50- to 100-fold higher affinities than the Smac AVPI peptide. Phase 1.

Catalog No. NC1665743


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