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ABclonal Technology ATAD3A/B Rabbit mAb
Supplier: ABclonal Technology A23184100UL
This gene encodes a ubiquitously expressed mitochondrial membrane protein that contributes to mitochondrial dynamics nucleoid organization protein translation cell growth and cholesterol metabolism This gene is a member of the ATPase family AAA-domain containing 3 gene family which in humans includes two other paralogs Naturally occurring mutations in this gene are associated with distinct neurological syndromes including Harel-Yoon syndrome High-level expression of this gene is associated with poor survival in breast cancer patients A homozygous knockout of the orthologous gene in mice results in embryonic lethality at day 7 5 due to growth retardation and defective development of the trophoblast lineage Alternative splicing results in multiple transcript variants [provided by RefSeq Feb 2017]
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