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Apexbio Technology LLC atorvastatin(Synonyms: Lipitor, Atorvastatin calcium, Sortis, Torvast, Atorva, Tahor, Zarator, Atorlip, Lipvas, Ator, Tulip), 500mg, CAS: 134523-00-5.
Supplier: Apexbio Technology LLC C6405500
Atorvastatin (CAS 134523-00-5) is an orally bioavailable inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase the enzyme catalyzing the rate-limiting step of cholesterol biosynthesis via the mevalonate pathway Beyond its cholesterol-lowering activity atorvastatin can modulate cardiovascular processes independently of lipid reduction primarily through inhibiting small GTPases such as Ras and Rho known contributors to cardiovascular pathology and vascular dysfunction Additionally atorvastatin has demonstrated inhibition of abdominal aortic aneurysm development by interfering with endoplasmic reticulum stress signaling pathways This molecule is frequently used in biomedical studies involving cholesterol metabolism vascular cell biology and cardiovascular disease research
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