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Cayman Chemical AureobasIdIn A 10mg

Supplier: Cayman Chemical 3972210 MG
A cyclic depsipeptide with diverse biological activities; inhibits inositol phosphorylceramide synthase (Kis = 0.18 and 0.23 for the C. albicans and S. cerevisiae enzymes, respectively); inhibits P-gp (IC50 = 2.27 µM); active against various mammalian pathogenic fungi, including Candida and Cryptococcus (MICs = S. cerevisiae (MIC = 0.4 UG/ml); increases survival in a mouse model of candidiasis induced by C. albicans at 80 mg/kg, p.o.
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