Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000064325

Apexbio Technology LLC AUY922 (NVP-AUY922) 747412-49-3 5mg
SDP

Supplier:  Apexbio Technology LLC A40575

Encompass_Preferred

AUY922 (NVP-AUY922 CAS 747412-49-3) is a synthetic small molecule inhibitor belonging to the resorcinylic isoxazole amide class that selectively targets heat shock protein 90 (HSP90) AUY922 specifically interacts with the ATP-binding site of the HSP90 N-terminal domain disrupting its chaperone-dependent stabilization of client proteins involved in cell proliferation and survival It demonstrates antiproliferative activity against human gastric cancer cells with reported GI50 values ranging approximately from 2 to 40 nmol/L promoting the proteasomal degradation of receptor tyrosine kinases and other relevant client proteins This compound is widely used in preclinical research settings investigating HSP90-dependent signaling pathways in cancer

Catalog No. 50-000-64325


May include imposed supplier surcharges.
Only null left
Add to Cart

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.