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Medchemexpress LLC AUZ 454 | 853299-07-7 | 99.2% | 501.50 | 100 MG
Supplier: Medchemexpress LLC HY15004100MG
AUZ 454 is a type II CDK2 inhibitor with a Kd of 8.2 nM. It inhibits CDK2 activity by competing with the binding of activating cyclins. It shows an inhibitory effect on Caki-1 and ACHN cells with WTAP overexpression and decreases colony formation through a CDK2-dependent mechanism. This product is intended for research use only.
- Inhibits CDK2 activity
- Competes with activating cyclins
- Inhibits cell proliferation in Caki-1 and ACHN cells
- Decreases colony formation in Caki-1 and ACHN cells
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