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Medchemexpress LLC AZD 9272 | 327056-26-8 | 99.9% | 284.22 | 1 MG
Supplier: Medchemexpress LLC HY11025410MG
AZD 9272 is a selective, orally active, and brain penetrant mGluR5 antagonist. It demonstrates high selectivity over other mGlu receptors and is intended for research use only. This compound causes a concentration-dependent decrease in the intracellular Ca2+ response in mGluR5 expressing cell lines.
- Selective mGluR5 antagonist
- Orally active and brain penetrant
- Shows >3900-fold selectivity over other mGlu receptors
- Causes concentration-dependent decrease in intracellular Ca2+ response
- Completely reverses glutamate-stimulated phosphatidyl inositol hydrolysis
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