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Selleck Chemical LLC AZD3229 S8780-5MG
Supplier: Selleck Chemical LLC S87805MG
AZD3229 is a potent pan-Kit (c-Kit) mutant inhibitor with potent single digit nM growth inhibition against a diverse panel of mutant Kit (c-Kit) driven Ba/F3 cell lines (GI50 1-50 nM) with good margin to KDR-driven effects It also inhibits PDGFR mutants (Tel-PDGFR Tel-PDGFR V561D/D842V)
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