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Apexbio Technology LLC AZD3839 1227163-56-5 10mg
Supplier: Apexbio Technology LLC B322410
AZD3839 (CAS 1227163-56-5) is a small-molecule inhibitor targeting BACE1 ( -site APP cleaving enzyme 1) It is designed to inhibit BACE1 thereby reducing amyloid (A ) peptide production implicated in Alzheimer s disease pathology AZD3839 exerts its biological activity primarily through inhibition of human BACE1 enzyme activity In cell-based studies AZD3839 demonstrates reduction of soluble amyloid precursor protein beta (sAPP ) and A 40 secretion in neuronal cellular models including human SH-SY5Y cells mouse neuroblastoma N2A cells and primary cortical neurons from mice and guinea pigs Based on these pharmacological properties AZD3839 holds research potential in Alzheimer s disease studies
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