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Medchemexpress LLC AZD5904 | 618913-30-7 | 99.9% | 252.29 | 25 MG
Supplier: Medchemexpress LLC 25MGHY111341
AZD5904 is a selective and irreversible inhibitor of human Myeloperoxidase (MPO) with an IC50 of 140 nM and has similar potency in mouse and rat. It demonstrates 10 to 19-fold selectivity compared to closely related lactoperoxidase and thyroid peroxidase, and >70-fold selectivity to a broad panel of other enzymes, ion channels, and receptors.
- Selective and irreversible inhibitor of human Myeloperoxidase (MPO)
- IC50 of 140 nM
- Similar potency in mouse and rat
- Highly selective compared to lactoperoxidase and thyroid peroxidase
- Highly selective compared to other enzymes, ion channels, and receptors
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