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Medchemexpress LLC Azide-PEG8-alcohol | 352439-36-2 | 97.0% | C16H33N3O8 | 100 MG
Supplier: Medchemexpress LLC HY140799100MG
Azide-PEG8-alcohol is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent due to its Azide group, which facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules containing Alkyne groups. It can also engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules possessing DBCO or BCN groups. PROTACs consist of two distinct ligands linked together, one targeting an E3 ubiquitin ligase and the other for a target protein, leveraging the intracellular ubiquitin-proteasome system to selectively degrade target proteins. This product is intended for research use only.
- PEG-based PROTAC linker
- Click chemistry reagent
- Facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions
- Engages in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
- Used in PROTAC synthesis
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