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Medchemexpress LLC Azido-PEG12-acid | 2152679-71-3 | 99.8% | C27H53N3O14 | 50 MG

Supplier: Medchemexpress LLC HY14045650MG
Azido-PEG12-acid is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent containing an Azide group, enabling both copper-catalyzed azide-alkyne cycloaddition (CuAAc) with Alkyne groups and strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups. PROTACs leverage the ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent with Azide group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Participates in strain-promoted alkyne-azide cycloaddition (SPAAC)
- PROTACs utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins
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