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Medchemexpress LLC Azido-PEG2-C6-Cl | 2568146-55-2 | 95.0% | 249.74 | 100 MG
Supplier: Medchemexpress LLC HY138470100MG
Azido-PEG2-C6-Cl is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It also functions as a click chemistry reagent, featuring an Azide group that can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. PROTACs themselves contain two different ligands connected by a linker; one targets an E3 ubiquitin ligase and the other targets a specific protein, utilizing the intracellular ubiquitin-proteasome system for selective protein degradation.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent with Azide group
- Undergoes copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc)
- Participates in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
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