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Medchemexpress LLC Azido-PEG5-CH2CO2-NHS | 2144777-77-3 | C16H26N4O9 | 100 MG

Supplier: Medchemexpress LLC HY140766100MG
Azido-PEG5-CH2CO2-NHS is a PEG-based PROTAC linker designed for synthesizing PROTACs. It features an Azide group, enabling click chemistry reactions like copper-catalyzed azide-alkyne cycloaddition (CuAAc) with Alkyne-containing molecules, and strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups.
- Can be used in the synthesis of PROTACs
- Contains an Azide group for click chemistry reactions
- Undergoes copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups
- Exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins
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