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Medchemexpress LLC Bardoxolone | 218600-44-3 | MFCD07772296 | 99.5% | 491.66 | 1 ML

Supplier: Medchemexpress LLC HY1490910MM/1ML
Bardoxolone (CDDO; RTA 401) is a potent Nrf2 activator, exhibiting anti-SARS-CoV-2 3CLpro activity and inhibiting the NF-κB pathway. It is known to induce cell differentiation and apoptosis, and shows antiproliferative activity against various cancer cells. This compound is valuable for research in fields such as cancer, inflammation, and infections like SARS-CoV.
- Activates Nrf2 pathway
- Inhibits NF-κB pathway
- Exhibits anti-SARS-CoV-2 3CLpro activity
- Induces cell differentiation and apoptosis
- Shows antiproliferative activity against cancer cells
- Increases ROS and decreases intracellular GSH levels
- Inhibits necroptosis
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