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Medchemexpress LLC Baricitinib | 1187594-09-7 | C16H17N7O2S | 50 MG
Supplier: Medchemexpress LLC HY15315R50MG
Baricitinib is a selective and orally bioavailable inhibitor of JAK1 and JAK2, widely used in research for its role in epigenetic and JAK/STAT signaling pathways.
- Selective JAK1 and JAK2 inhibitor
- Molecular weight of 371.42
- Inhibits IL-6-stimulated STAT3 phosphorylation
- Prevents IL-23 stimulated production of IL-17 and IL-22 by Th17 cells
- Active in vivo, reducing inflammation and hind paw volumes in animal models
- Stable as a powder for 3 years at -20°C, 2 years at 4°C
- Stable in solvent for 1 year at -80°C, 6 months at -20°C
- Soluble in DMSO (in vitro) and various solutions for in vivo applications
- Solid appearance
- Melting point 212-215°C
- Relative density 1.56 g/cm³
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