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Enzo Life Sciences BAY 61-3606. hydrochloride (25mg). CAS: 648903-57-5

Supplier: Enzo Life Sciences ALX270479M025

Cell permeable, potent, ATP-competitive and reversible inhibitor of spleen tyrosine kinase (Syk) (IC50=10nM). Highly selective if compared to other kinases; shows no inhibitory effect against Btk, Fyn, Itk, Lyn, and Src up to concentrations of 4.7µM. Anti-inflammatory and orally active. Exhibits good in vivo efficacy in the treatment of various allergy and asthma conditions in rat models. Alternative name: 2-[[7-(3,4-Dimethoxyphenyl)imidazo[1,2-c]pyrimidin-5-yl]amino]pyridine-3-carboxamide . HCl. Purity: ≥98% (HPLC(UV)). Solubility: Soluble in water (30mg/ml), DMSO (2mg/ml) or methanol (1mg/ml). Long Term Storage: -20°C.
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