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Medchemexpress LLC BDP9066 | 2226507-04-4 | 98.2% | 348.44 | 10 MG
SDP

Supplier:  Medchemexpress LLC HY11142410MG

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BDP9066 is a potent and selective myotonic dystrophy-related Cdc42-binding kinase MRCK inhibitor. It has an IC50 of 64 nM for MRCKβ in SCC12 cells, and Ki values of 0.0136 nM and 0.0233 nM for MRCKα/β respectively. It demonstrates a therapeutic effect on skin cancer by reducing substrate phosphorylation. This product is for research use only.

  • Targets MRCKα (0.0136 nM (Ki)) and MRCKβ (0.0233 nM (Ki))
  • Shows antiproliferative effects with greatest activity in hematologic cancer cells
  • Inhibits MLC phosphorylation and blocks SCC12 squamous cell carcinoma motility and invasion
  • Topical application significantly decreases phosphorylated MRCKα S1003 staining and tumor volumes

Catalog No. 50-003-46183


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