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Medchemexpress LLC Beclomethasone 17-propionate | 5534-18-9 | 99.5% | 464.98 | 1 ML
SDP

Supplier:  Medchemexpress LLC HY13623910MM/1ML

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Beclomethasone 17-propionate is an active metabolite of Beclomethasone dipropionate and acts as a glucocorticoid receptor (GR) agonist. It demonstrates a higher affinity for GR compared to Beclomethasone dipropionate and is effective in suppressing cytokine production in lung macrophages of individuals with chronic obstructive pulmonary disease (COPD).

  • Metabolism of beclomethasone dipropionate to 17-BMP is a crucial activation step.
  • Inhibits LPS-stimulated CXCL8, TNFα, and IL-6.
  • Upregulates GR-dependent genes FKBP51 and GILZ.

Catalog No. 50-003-50952


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