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Cayman Chemical BelvarafenIb 10mg
SDP

Supplier:  Cayman Chemical 3146010 MG

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An ER proteostasis regulator activates an ATF6-dependent ER stress response element reporter and antioxidant response element reporter in HT22 hippocampal cells (EC50s 3 6 and 3 92 UM respectively) and protects against glutamate-induced cytotoxicity and prevents increases in ROS in HT22 cells at 10 UM reduces tunicamycin-induced cell death and increases ERAD in neonatal rat ventricular myocytes at 10 UM reduces the myocardial renal and cerebral infarct size as a percentage of the area at risk in mouse models of ischemia-reperfusion injury induced by LAD ligation renal portal system occlusion or MCAO respectively at 2 mg/kg prevents the production of NS5 in dengue virus-infected Huh7 cells (IC50 1 UM)

Catalog No. 50-299-2100


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