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Medchemexpress LLC Bendamustine hydrochloride | 3543-75-7 | 99.9% | C16H22Cl3N3O2 | 500 MG
Supplier: Medchemexpress LLC HYB0077500MG
Bendamustine hydrochloride is a purine analogue and a DNA cross-linking agent. It activates DNA-damage stress response and apoptosis, demonstrating potent alkylating, anticancer, and antimetabolite properties. This compound has been shown to reduce the viability of multiple myeloma cell lines and to induce specific caspase-dependent cell death.
- Functions as a DNA cross-linking agent
- Activates DNA-damage stress response and apoptosis
- Possesses potent alkylating, anticancer, and antimetabolite properties
- Reduces viability of multiple myeloma cell lines
- Induces specific caspase-dependent cell death
- Causes DNA breaks
- Regulates apoptosis and DNA repair pathways in non-Hodgkin's lymphoma cells
- Blocks mitotic checkpoints and causes mitotic catastrophe
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