Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC Benserazide hydrochloride | 14919-77-8 | 99.7% | 10 MM 1 ML
Supplier: Medchemexpress LLC HYB0404A10MM/1ML
Benserazide hydrochloride (Serazide) is an aromatic L-amino acid decarboxylase (AADC) and L-DOPA decarboxylase inhibitor. It also acts as a PKM2 inhibitor by directly binding to and blocking PKM2 enzyme activity, leading to inhibition of aerobic glycolysis and concurrent up-regulation of OXPHOS. This compound is suitable for research related to Parkinson's disease and melanoma.
- Acts as an aromatic L-amino acid decarboxylase (AADC) and L-DOPA decarboxylase inhibitor.
- Inhibits PKM2 enzyme activity.
- Inhibits aerobic glycolysis and up-regulates OXPHOS.
- Supports research in Parkinson's disease and melanoma.
- Inhibits protein aggregation and minimizes amyloid-induced cytotoxicity in human neuroblastoma cell line SH-SY5Y.
- Increases exogenous L-DOPA-derived extracellular DA levels in 6-OHDA-lesioned male Wistar rats.
- Reduces central AADC activity in the striatum of rats with nigrostriatal denervation.
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?