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Medchemexpress LLC Benserazide (hydrochloride) | 14919-77-8 | MFCD00078571 | >98.0% | 5 G
Supplier: Medchemexpress LLC HYB0404A5G
Benserazide hydrochloride, also known as Serazide, is an aromatic L-amino acid decarboxylase (AADC) and L-DOPA decarboxylase inhibitor. It also acts as a PKM2 inhibitor by directly binding to and blocking PKM2 enzyme activity, which leads to the inhibition of aerobic glycolysis and concurrent up-regulation of OXPHOS. This compound is valuable in the study of Parkinson's disease and melanoma.
- Inhibits L-amino acid decarboxylase and L-DOPA decarboxylase.
- Acts as a PKM2 inhibitor by directly binding to and blocking its enzyme activity.
- Leads to inhibition of aerobic glycolysis and concurrent up-regulation of OXPHOS.
- Valuable in the study of Parkinson's disease.
- Applicable in melanoma studies.
- Target: Pyruvate kinase.
- Pathway: Metabolic enzyme/protease.
- Soluble in DMSO (100 mg/mL) and water (≥ 50 mg/mL).
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