Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000352084

Medchemexpress LLC Benzeneethanamine, 3,4-dimethoxy-N-methyl-N-[3-[4-[[1-methyl-2-(1-methylethyl)-1H-indol-3-yl]sulfonyl] | 121345-64-0 | 99.8% | 564.74 | 50 MG
SDP

Supplier:  Medchemexpress LLC HY13690950MG

Encompass_Preferred

SR33805 is a potent Ca2+ channel antagonist with EC50s of 4.1 nM and 33 nM in depolarized and polarized conditions, respectively. It selectively blocks L-type but not T-type Ca2+ channels, making it suitable for research on acute or chronic failing hearts.

  • Potent Ca2+ channel antagonist.
  • Selectively blocks L-type Ca2+ channels.
  • Useful for research on acute or chronic failing hearts.
  • Inhibits growth factor-induced proliferation of smooth muscle cells (SMC) in vitro in a dose-dependent manner.
  • Restores myocardial infarction (MI)-altered cell shortening without affecting Ca2+ transient amplitude in vitro.
  • Improves end-systolic strain and fractional shortening of MI hearts in rats in vivo.
  • Significantly reduces intimal hyperplasia in pigs in vivo.

Catalog No. 50-003-52084


May include imposed supplier surcharges.
Only null left
Add to Cart

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.