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Medchemexpress LLC Benzenesulfonamide, 2,4-difluoro-N-[2-methoxy-5-[4-[3-[4-(methylsulfonyl)-1-piperazinyl]-1- | 1676893-24-5 | 100.0% | 627.68 g·mol⁻¹ | C29H27F2N5O5S2 | 100 MG

Supplier: Medchemexpress LLC HY100470100MG
NSC781406 is a small-molecule dual inhibitor of phosphoinositide 3-kinase (PI3K) and mechanistic target of rapamycin (mTOR) for research use. It exhibits low-nanomolar enzymatic potency and cellular antiproliferative activity, and has shown antitumor efficacy in preclinical xenograft models.
- Potent PI3Kα inhibition (IC50 2 nM).
- Dual PI3K/mTOR activity (mTOR IC50 5.4 nM).
- Broad cellular antiproliferative activity across cancer cell lines.
- High chemical purity (99.97%).
- Solid form for standard laboratory handling.
- Supplied as a 100 mg research package.
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