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Medchemexpress LLC Benzoic acid, 3-chloro-4-cyano-, 2-[4-cyano-2-(trifluoromethyl)phenyl]hydrazide | 2361742-30-3 | 99.9% | C16H8ClF3N4O | 1 ML
SDP

Supplier:  Medchemexpress LLC HY14487810MM/1ML

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VPC-70619 is a potent N-Myc inhibitor that blocks the binding of the N-Myc-Max heterocomplex to the DNA E-box. It demonstrates potent inhibitory activity against N-Myc-dependent cell lines and can partially reverse paclitaxel resistance in cells by reducing MYCN expression. It is suitable for cancer research, including neuroblastoma and thyroid cancer.

  • Potent N-Myc inhibitor
  • Blocks binding of N-Myc-Max heterocomplex to DNA E-box
  • Potent inhibitory activity against N-Myc-dependent cell lines
  • Can partially reverse paclitaxel resistance by reducing MYCN expression
  • Suitable for cancer research
  • High stability in liver microsomes
  • Upregulates MYCN, MDM2, and CRABP2 mRNA levels
  • Downregulates TGM2 and INHBA
  • Inhibits proliferation, migration, and aggressiveness of SW1736-PTX and 8505C-PTX cells

Catalog No. 50-003-55891


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